Is it possible to trigger a method when a data member has changed in BindingSource?

Hi, all:

I have a datagridview that some properties binding with a BindingSource members, like:

this.dataGridView1.DataBindings.Add(new System.Windows.Forms.Binding("Enabled", this.myBindingSource, "IsEnabled", true));

Now, I want to call a extension method in datagridview when "IsEnabled" has value changed, is it possible to that?

Thanks for your kind reply in advance.